MolOps.h File Reference

#include <RDGeneral/types.h>
#include <boost/tuple/tuple.hpp>

Go to the source code of this file.

Namespaces

namespace  RDKit
namespace  RDKit::MolOps

Typedefs

typedef std::vector
< double > 
RDKit::INVAR_VECT
typedef
INVAR_VECT::iterator 
RDKit::INVAR_VECT_I
typedef
INVAR_VECT::const_iterator 
RDKit::INVAR_VECT_CI
typedef
boost::tuples::tuple
< double, double,
double > 
RDKit::DiscrimTuple
 used to return atomic discriminators (three doubles)

Enumerations

enum  RDKit::AtomInvariantType { RDKit::ComprehensiveInvariants, RDKit::ChiralSearchInvariants }
 used to request particular types of atom invariants More...

Functions

unsigned int RDKit::MolOps::getMolFrags (const ROMol &mol, INT_VECT &mapping)
 find fragments (disconnected components of the molecular graph)
unsigned int RDKit::MolOps::getMolFrags (const ROMol &mol, VECT_INT_VECT &frags)
 find fragments (disconnected components of the molecular graph)
ROMol * RDKit::MolOps::addHs (const ROMol &mol, bool explicitOnly=false, bool addCoords=false)
 returns a copy of a molecule with hydrogens added in as explicit Atoms
ROMol * RDKit::MolOps::removeHs (const ROMol &mol, bool implicitOnly=false, bool updateExplicitCount=false, bool sanitize=true)
 returns a copy of a molecule with hydrogens removed
ROMol * RDKit::MolOps::mergeQueryHs (const ROMol &mol)
int RDKit::MolOps::countAtomElec (const Atom *at)
 return the number of electrons available on an atom to donate for aromaticity
int RDKit::MolOps::setAromaticity (RWMol &mol)
 Sets up the aromaticity for a molecule.
void RDKit::MolOps::cleanUp (RWMol &mol)
 Designed to be called by the sanitizer to handle special cases before anything is done.
void RDKit::MolOps::adjustHs (RWMol &mol)
 adjust the number of implicit and explicit Hs for special cases
int RDKit::MolOps::findSSSR (const ROMol &mol, VECT_INT_VECT &res)
 finds a molecule's Smallest Set of Smallest Rings
int RDKit::MolOps::findSSSR (const ROMol &mol, VECT_INT_VECT *res=0)
int RDKit::MolOps::symmetrizeSSSR (ROMol &mol, VECT_INT_VECT &res)
 symmetrize the molecule's Smallest Set of Smallest Rings
void RDKit::MolOps::Kekulize (RWMol &mol, bool markAtomsBonds=true, unsigned int maxBackTracks=100)
 Kekulizes the molecule.
void RDKit::MolOps::setConjugation (ROMol &mol)
 flags the molecule's conjugated bonds
bool RDKit::MolOps::atomHasConjugatedBond (const Atom *at)
 returns whether or not the given Atom is involved in a conjugated bond
void RDKit::MolOps::setHybridization (ROMol &mol)
 calculates and sets the hybridization of all a molecule's Stoms
void RDKit::MolOps::sanitizeMol (RWMol &mol)
 carries out a collection of tasks for cleaning up a molecule and ensuring that it makes "chemical sense"
double * RDKit::MolOps::getAdjacencyMatrix (const ROMol &mol, bool useBO=false, int emptyVal=0, bool force=false, const char *propNamePrefix=0)
 returns a molecule's adjacency matrix
double * RDKit::MolOps::getDistanceMat (const ROMol &mol, bool useBO=false, bool useAtomWts=false, bool force=false, const char *propNamePrefix=0)
 Computes the molecule's topological distance matrix.
double * RDKit::MolOps::getDistanceMat (const ROMol &mol, const std::vector< int > &activeAtoms, const std::vector< const Bond * > &bonds, bool useBO=false, bool useAtomWts=false)
 Computes the molecule's topological distance matrix.
INT_LIST RDKit::MolOps::getShortestPath (const ROMol &mol, int aid1, int aid2)
 Find the shortest path between two atoms.
DiscrimTuple RDKit::MolOps::computeDiscriminators (const ROMol &mol, bool useBO=true, bool force=false)
 calculates a set of molecular discriminators from the distance matrix
DiscrimTuple RDKit::MolOps::computeDiscriminators (double *distMat, int nb, int na)
 Same as MolOps::computeDiscriminators(const ROMol &mol), except that this directly uses the user-supplied distance matrix.
double RDKit::MolOps::computeBalabanJ (const ROMol &mol, bool useBO=true, bool force=false, const std::vector< int > *bondPath=0, bool cacheIt=true)
 calculates Balaban's J index for the molecule
void RDKit::MolOps::findSpanningTree (const ROMol &mol, INT_VECT &mst)
 finds a molecule's minimium spanning tree (MST)
void RDKit::MolOps::rankAtoms (const ROMol &mol, INT_VECT &ranks, AtomInvariantType invariantType=ComprehensiveInvariants, bool breakTies=true, VECT_INT_VECT *rankHistory=0, bool includeChirality=false)
 assign a canonical ordering to a molecule's atoms
void RDKit::MolOps::buildAtomInvariants (const ROMol &mol, INVAR_VECT &res, bool includeChirality=false)
 calculates a set of atom invariants
void RDKit::MolOps::buildChiralAtomInvariants (const ROMol &mol, INVAR_VECT &res)
 calculates a set of chiral atom invariants
void RDKit::MolOps::assignAtomChiralCodes (ROMol &mol, bool cleanIt=false, bool force=false)
 calculate CIP (R/S) codes for a molecule's chiral centers
void RDKit::MolOps::assignBondStereoCodes (ROMol &mol, bool cleanIt=false, bool force=false)
 calculate CIP (Z/E) codes for a molecule's double bonds
void RDKit::MolOps::findPotentialStereoBonds (ROMol &mol, bool cleanIt=false)
 finds bonds that could be cis/trans in a molecule and mark them as Bond::STEREONONE
int RDKit::MolOps::getFormalCharge (const ROMol &mol)
 sums up all atomic formal charges and returns the result
void RDKit::MolOps::cleanupChirality (RWMol &mol)
 removes bogus chirality markers (those on non-sp3 centers):

Variables

const int ci_LOCAL_INF


Variable Documentation

const int ci_LOCAL_INF


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